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Data & Mappings
Ecce Homology is created from data from the human genome dataset and from the rice plant genome dataset.
Figure:Orientation of genomic calligraphy created from human sequences and rice plant sequences in Ecce Homology. Rice genome is along the horizontal axis, and human genome sequences are along the vertical axis. The central region is left open, as a "gap" to contain the selected human sequence that is the query in the BLAST analysis to compare against the rice target genome.
Figure:Early sketching for calligraphic strokes.
Figure: Left: Standard representation of three dimensional structure of amylase based on the atomic coordinates deposited in the protein data bank. Rendered with Pymol (Delando, 2002). Middle and Right: Genomic calligraphy pictographs of protein sequence for human and rice amylase.
Video ( 2:25 duration) Genomic calligraphy and pictograph concept, design and data mapping.
Figure: Calligraphic brush model profile is determined by nucleotide percentages.
Figure: caption text
Video ( 37 secpmds duration) Visualization of the BLAST algorithm operating in Ecce Homology. The sequence from the top vertical pictograph (human genome sequences) is selected for comparative analysis with the sequences represented on the horizontal axis (rice genome sequences). In this instance, there is homology identified between the human and rice sequences. The homolog is indicated by an overaly of the matched calligraphic pictographs, the projected overlay fades and smears over the course of the day in the gallery. If there is no homology between the two sequences being compared, there will not be an overlap presented. In the installation, over the course of each day of the exhibition, the sequences that had been analyzed via BLAST and where homology had been identified, retained traces of of the matches. This persists throughout the day and resets for the next exhibition day.
- DeLano, WL (2002) The PyMOL molecular graphics system. DeLano Scientific, San Carlos California.
